The Week 2 schedule features 15 Big Ten games, with Washington (-24.5) vs. Eastern Michigan among the best bets against the spread, based on our projections. For more suggestions, including parlay opportunities, keep reading.

Take a look at our Week 2 college football odds breakdown.

The best Big Ten spread bets from Week 2

College football odds are offered by BetMGM sports betting. Odds were last updated Wednesday at 11:36 PM ET. For a complete list of sports betting odds, visit the USA TODAY Sports Betting Scores Odds Hub.

Pick: Take Washington -24.5 over Eastern Michigan

  • Game Information: Eastern Michigan Eagles at Washington Huskies
  • Projected Winner: Washington with 46.3 points
  • Game time: 3:30 PM ET
  • Game date: September 7
  • TV channel: BTN
  • Live stream: Fubo

Pick: Take Michigan +7.5 over Texas

  • Game Information: Texas Longhorns at Michigan Wolverines
  • Projected Winner: Michigan by 7 points
  • Game time: 12:00 PM ET
  • Game date: September 7
  • TV channel: FOX
  • Live stream: Fubo

Pick: Take Duke +2.5 over Northwestern

  • Game Information: Duke Blue Devils at Northwestern Wildcats
  • Projected Winner: Duke by 5.2 points
  • Game time: 9 p.m. ET
  • Game date: September 6
  • TV channel: Fox Sports 1
  • Live stream: Fubo

Pick: Take Kansas -5.5 over Illinois

  • Game Information: Kansas Jayhawks at Illinois Fighting Illini
  • Projected Winner: Kansas by 12.5 points
  • Game time: 7 p.m. ET
  • Game date: September 7
  • TV channel: Fox Sports 1
  • Live stream: Fubo

Pick: Take Maryland -9.5 over Michigan State

  • Game Information: Michigan State Spartans at Maryland Terrapins
  • Projected Winner: Maryland with 14.8 points
  • Game time: 3:30 PM ET
  • Game date: September 7
  • TV channel: BTN
  • Live stream: Fubo

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